of oedematous deposit in the anterior mediastinum. Left lung: pleura and pericardium normal.

Goat No. 16.

6*7*22. Inoculated into right lung with 3 c.c. of citrated pleuritic fluid, from an acute case of Infectious Pleuro-pneumonia (goat 14), which had been passed through a porcelain filter. (Berkfelt).

22-7-1922 Maximum temperature 104°2F.

23-7- „ ? 9 99 105°2F.

24-7- „ ? 9 9) 107°F.

25-7- „ »9 t 9 107°2F.

26-7- „ >9 9} 107°6F.

27-7- ,, 9 > 9 9 107°4F.

28-7- „ i y 9 9 107°2F.

29-7- „ 99 99 107°F.

30-7- „ 99 99 105°F. 3T7- „ 9 9 9 9 104° F.

1-8- ,, .Normal During the period of fever the goat was very dull, lying down. Ate very little. Respirations slightly accelerated but no symptoms of Pneumonia or Pleurisy. The rise of temperature commenced on the 16th. day after inoculation.

The goat was kept under observation for six weeks and destroyed.

Post-mortem, Lungs, pleura and pericardium normal.

Goat No. 17.

6-7-22. Inoculated into right lung with 2 c.c. of a suspension in sterile salt solution of a scraping from a hepatised lung of an acute case of Infectious Pleuro-pneumonia (goat 14). Before the inoculate n the suspension was well shaken and then passed through a porcelain filter. (Berkfelt).

22- 7-1922. Maximum temperature 103°4F.

23- 7- M „ „ 105°F.

24- 7- „ „ „ 103°2F.

25- 7- ,, Normal. This was a very slight reaction, but it occurred on the loth, day after the inoculation. This goat was kept under observation and then destroyed.

Post-mortem. Lungs, pleura and pericardium normal.

From these experiments the following conclusions are suggested : 1. That Infectious Pleuro-pneumonia of goats is caused by an ttltra*visible virus (see goats 16 and 17).

2. That the lung lesions are due to a secondary invader, probably a Pasteurella-