tn the investigation of the etiology of this disease, the following inoculations were carried out. All the goats used for these experi¬ ments were healthy, half-grown goats in good condition.

Goat No. J.

17-5-22. Cotton swabs soaked in the nasal discharge from goat No. 4, an acute case of Infectious Pleuro-pneumonia, were pushed in the nostrils of this goat. Daily observations of temperature and condition were made.

1-6-22* On this day i.e. the 16th. day after infection, the temperature rose to 106°F. The goat stopped eating and was lying down the whole day. Respirations were slightly accelerated but otherwise there were no symptoms of pleurisy or pneumonia.

2- 6-22. Maximum temperature 107°6F.

3- 6-22. „ „ 106°6F.

4- 6-22. ,, ,, 105°2F. Destroyed.

During these four days the goat ate very little, and rapidly lost condition, but on the fourth day appeared to be improving a little.

Post-mortem. A slight excess of pericardial fluid (l oz). Lungs and pleura normal.

Goat No. 12.

22-6-22, Inoculated with 2 c.c. of pleuritic fluid from an acute case of Infectious Pleuro-pneumonia (goat 11) into the right lung.

27- 6-22. Temperature 107°F. Very dull. Loss' of appetite. Respirations slightly accelerated.

28- 6-22 to 30-6-22. Temperature 107°F.

1-7-22. Temperature 1069F. Destroyed.

Post-mortem. Right lung normal. Right pleura contained about 2 oz. of clear fluid. Left lung, pleura and pericardium normal.

Goat No. 13.

22-6-22. Inoculated into right lung with 2 c.c. of a suspension in sterile salt solution of a scraping from the cut surface of a hepatised lung from an acute case of Infectious Pleuro-pneumonia fgoat 11).

27*6-22. Temperature 107°F., with symptoms of acute Pleuro¬ pneumonia. Temperature remained at 107°F until 1-7-22, when it was destroyed. During these four days the goat ate very little and rapidly lost condition.

Post-mortem. Right lung: practically the entire lung was in a state of red hepatisation, with a centre of commencing grey hepatisation. Right pleura; about 4 oz. of a slightly turbid fluid. A quantity