Sudan Archive

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On the 6th, 8th, 10th and 12th November, the following injections Were given intravenously 3i grammes of Picric Acid and 4 grammes of Atoxyl. On the 20th November the Trypanosomes reappeared in the blood.

The animal continued to lose condition and had to be destroyed.

Cases (v) and (vi), These were two camels of natural infection with Trypanosome soudanense, both sent from Wad Medani.

They were both typical cases of chronic camel Trypanosomiasis in the Sudan, with sub-acute phases of the disease, during which there s a rise of temperature and Trypanosomes appear in the blood.

Both were given a course of four doses of Tartar Emetic and Picric Acid administered intravenously every other day.

The following doses were given each day 4 4 grammes of Picric Acid (4 grammes alcoholic and i grammes aqueous sol.) and 30 c.c. of 4% solution of Tartar Emetic.

The blood of both camels remained free from Trypanosomes for a month, and improved in condition, but at the end of a month Trypanosomes reappeared in the blood.

Case (vii).

This was a case of natural infection with the Trypanosoma soudanense. It was treated with a combination of Atoxyl and Picric Acid.

6 grammes of' Atoxyl in 60 c.c. of water, and grammes of Picric Acid were given intravenously every other day for four doses.

Again the blood stream remained free of Trypanosomiasis for about one month, when Trypanosomes appeared in the blood, Summary.

From the above, it will be seen that the treatment of equines affected with Trypanosoma pecaudi and camels affected with Tryp¬ anosoma soudanense, with combinations of Tartar Emetic and Picric Acid, and Atoxyl and Picric Acid was unsuccessful.

On the other hand treatment with Picric Acid and Tartar Emetic of equines (cases (i) and (ii) I affected with Trypanosoma nanum was successful. .

It is known that Trypanosomiasis ol cattle, due to infection with T. congoleuse. can be treated with Tartar Emetic alone, but equines infected with congoleuse or nanum have not been successfully treated with Tartar Emetic alone.

It would therefore appear that a step forward in the treatment of Trypanosomiasis of equines affected with Trypanosoma nanum has been made by these experiments,

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