W. E. Marshall
(2) It can be infected by intraperitoneal or by subcutaneous inoculation of the parasite.
(3) It can also be infected naturally, an uninoculated monkey, living in close contact with an infected monkey, having contracted the disease.
(4) The parasites are present in the peripheral blood of infected monkeys.
(5) So far we have found that the best method of infecting the monkey is by injecting into the peritoneal cavity the contents of a spleen puncture taken during life.
I beg to acknowledge my indebtedness to Captain D. S. B. Thomson, R.A.M.C., who was associated with me in investigating kala-azar in Sennar Province, for help and advice, and to Captain R. G. Archibald, R.A.M.C., for carrying on the experiments while we were both absent on leave.
LITERATURE.
ALVAREZ ET PEREIRA DA Sibva (1910). ‘ Sobre e l’existencia do kala-azar espontaneo no cdo em Lisboa,’’ Medicine Contemporanea, 22 di Maio, 1910, p. 162. BasizE (1910). ‘* Sulla Leishmaniosi del Cane e sull’ ospite intermedio del kala-azar infantile,’’ Rediconti della R. Accademia dei lincei, vol. xix, November 20, 1910, p. 523. Critien (1910). ‘ Kala-azar infantile & Malte.’’ Note préliminaire. Archiv. de I’ Inst. Past. de Tunis, 1910, vol. ii, p. 49. Gaps (1910). ‘‘Intorno al kala-azar. Il focolaio endemico di!Bordonaro. Studio clinico. Studi intorno ad alcune malattie tropicali della Callabria e della Sicilia. Sezione di malattie esotiche del R. Instituto di clinica medica di Roma,” Archiv. de VInst. Past. de Tunis, 1910, vol. i, Analyses, p. 46. Jemma (1909). ‘‘Sopra un caso di anemia splenica infantile da corpi di Leishman osservata a Palermo,” Archiv. de l’Inst. Past. de Tunis, 1910, vol. i, Analyses,
p. 45. ’ Jemma, Di OrisTina v. Cannata (1910). ‘‘ Hxperimentelle infektion mit ‘ Leishmania infantum’ bei Hunden,” Centralbl. f. Bakt., Bd. 57, Heft 1, December 17, 1910,
p. 59. LaverAN ET Perrir (1909). ‘Infections légéres du rat et de la souris par la Leish- mania donovani,’’ Compt. rend. Soc. Biol., 1909, vol. xvi, p. 911. LavERAN Et Perrit (1909). “‘ Infections expérimentales légéres ou latentes du singe et du chien par le kala-azar tunisien,” Bull. Soc. Path. Hxot., 1909, vol. ii, p. 584. Nicotite (1909). ‘Le kala-azar infantile,” Annales de VInst. Pastewr, vol. xxiii,
pp. 361 and 441. Nicoze (1910). - ‘‘ Etat actuel de la question du kala-azar infantile,” Archiv. de l’Inst. Past. de Tunis, 1910,.vol. iii, p. 109. Nicotue pr ComtTE (1909). ‘‘Kala-azar expérimental du chien,” Archiv. de Inst. Past. de Tunis, 1909, vol. iii, p. 136 ; and 1909, vol. iv, p. 199. Nico~te et Comte (1910). ‘ Kala-azar experimental du chien. Quelques observa- tions nouvelles et quelques faits nouveaux.’’ Immunité par premiére atteinte aprés guérison complete, Archiv. de l’ Inst. Past. de Tunis, 1910, vol. iii, p. 103. Nroonie et Mancravux (1909). ‘* Kala-azar expérimental du singe,” Archiv. de I’ Inst. Past. de Tunis, 1909, vol. iii, p. 133.